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Late presentation of leucoencephalopathy with calcifications and cysts Leucoencephalopathy with intracranial calcifications home and cysts(Lcc)Is a rare disorder of unknown origin characterised radiologically By white matter abnormalities, calcifications and cysts with contrast enhancing nodules.14 Neuropathology reveals"Angiomatouslike"Rearrangements of microvessels and rosenthal fibres(Rf).13 The onset is almost invariably in early infancy to adolescence.Occurrence of disease in siblings suggests autosomal recessiveand pyramidal signs.As some patients have visual disturbances http://www.flashgallery.co.uk/uk-women-s-ralph-lauren-outlet.html and retinal vascular abnormalities resembling coats' disease, 2 lcc has been linked to coats plus syndrome, a rare disease characterised by retinal vascular abnormalities, leucoencephalopathy And calcifications without brain cysts.2 5 Systemic involvement is common with haematological, enteric, dermatological or skeletal abnormalities.2 5 cheap ralph lauren uk We describe two sporadic patients with late onset LCC.



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